Top Definition
Verb. A side effect of extreme over indulgence in crystal meth or crack cocaine. Tweekers typically perform OCD-like activities centered around finding small quantities of drugs that were inadvertently "misplaced". Tweekers may be seen on all fours, searching in gutters, obsessively looking under various objects and so on. In certain circumstances, extreme tweeking resembles autism or catatonia.
Yo! Check out that tweeking crack ho!
door Slagathor 23 april 2004
A character from the TV show "South Park". Tweek is the ADD kid, who is constantly twitching. He often rants and raves about things that only he sees, and is addicted to coffee. Tweek is in love with Craig, and they sex each other.
Wow. Tweek sure has sex with Craig a lot. It's hot.
door The Lord Of Spam 16 februari 2006
losing oneself in a senseless task while under the influence of speed.
She would tweek all night cleaning the house and pulling apart electronic devices.
door chillcat 29 mei 2003
the nervous ticks or twitching one experiances as they come down from a crystal methamphetamine binge.
pulling hairs out of their face; picking at their face; picking their nose...
door a former tweeker 28 november 2003
Upper, crystal meth
can I have a bump of tweek?
door Cosmo Wash.DC 26 december 2002
to adjust or fix
Let me just tweek your computer.
door Tracy Lukeman 20 oktober 2003
When you can't twerk, so you have to push your buttcheeks up and down to make them look like they are bouncing.
Guy1: Is that girl twerking or what?
Guy2: Naw man she's tweeking...
door Uhhhhhh123 3 februari 2014

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