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1.
TLS
Third lung syndrome.

When, instead of a brain, a person has a third lung in the space where their brain should be. Unfortunatley, this means they have a bigger air capacity, allowing them to talk more, but because they have no brain, they don't have the ability to think through about what they're going to say first.

A common name for somebody with TLS is airhead. Which is ironic because lungs of course breathe in air.
Girl: Stands in pudddle. "OMG! Its like all wet and stuff!'
Guy: '*cough* TLS! *cough*'
Girl: 'Whaat?'
door Ishtar. 24 juli 2009
23 15
 
2.
TLS
commonly known as Team Light Skinned, theres are many restrictions on entry in this elite group.
john: Can I join TLS?

Tom: No bro you're too dark
door lil beebe 18 september 2012
8 5
 
3.
TLS
TLS stands for talking loud syndrome. if someone talks really loud all the time (or usually ) they have TLS. it is not TALKS loud syndrome. it is TALKING loud syndrome. TLS can be a side effect of headphone syndrome
Dean: hey sarah, why does kaie talk so loud?
Sarah: she has TLS.
Katie: YEAH! I HAVE TLS!!!! A LOT!!!
door justanotherpersonoverhereonud 6 maart 2007
11 13
 
4.
TLS
TLS stands for Tommy Lee Syndrome. That is, that the average tall, super skinny white guy is very well endowed in his manhood.
Girl 1: so, did you sleep with that tall, skinny guy from the bar?

Girl 2: yes, and I was totally thrilled that he suffers from TLS
door Special_K115 4 augustus 2009
8 14
 
5.
TLS
faghat, oftens eat count dracula for fun, "They Scrape your teeth"
eEeEKz
door anonymous 12 september 2003
3 27
 
6.
TLS
g0d or g0d
One who owns you
TLS is g0d
door anonymous 22 februari 2003
8 33