Top Definition
This expression is supposed to imply a juxtaposition of a crass or offensive action against something that is held as sacrosanct by someone else.

Coined by Ben "Yahtzee" Croshaw
"For four, what the fuck happened to Clive Winston, you pricks?! In his place we've got some multicoloured, giggly J-pop creature, and you can't play classic rock with that...thing. It's like cock-slapping the Mona Lisa."
-Ben "Yahtzee" Croshaw in his Guitar Hero III review
door Platitude 27 mei 2015
1 more definition
5 Words related to cockslapping the mona lisa
AS the title states it is the act in which the pennis is whacked furtively about the famous painting the "mona lisa" often resulting in architectural fapping.
Architect 1: Look that dude's cockslapping the mona lisa!

Architect 2: Yeah, you like that don't you baby?! *fap fap fap*
door Curtis Mortemer 23 juli 2008

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