Top Definition
one thousand dollars
I just bet two big ones on black jack.
door Teemuh 30 april 2008
3 more definitions
An extremely large bomb, often nuclear.
During the Cold War the United States was afraid that the Soviets would drop the big one.
door blenheimears 14 april 2009
a pleasantly large penis
I think my cervix is dented ... he has a BIGONE!
door carefulgirl 12 september 2006
code for a bundle of heroin- 10 bags, otherwise known as a bun
i copped a big one for eighty in paterson and flipped it for a buck twenny to some maricóns in westchester
door nothing where we go 31 december 2010

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