Top Definition
Also known as perma-smile.

To have a permanent smile on your face when you are under the influence of any drug or alcohol. Most likely, somebody will have a permasmile when they are on really good shrooms and suffer from uncontrollable laughter that seems to go on forever.
I was so trashed last night on shrooms that I had a permasmile and thought everything was funny.
door Citizen Insane 2 januari 2005

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The insincerely constant smiling expression on the face of a politician or other performer, which is meant to ingratiate oneself with voters/fans, as opposed to being a true expression of the person's feelings.
Headline of a political commentary article: "Mitt Romney: the man behind the perma-smile."

"Because she's always wearing that perma-smile, it's hard to know what's really going on with her.
door Mme K 21 september 2012

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