The acute onset of paranoia in otherwise normal people in reaction to the policies, the statements -- nay -- the very existence of Barack Obama.
Obama's positions better reflect the change and new direction that the American people have been calling for, but those with Obama Derangement Syndrome would rather stick with failure than even consider voting for him.
door ptulsa 16 mei 2008
The state of paranoia in which people fear President Obama so much, they stop thinking logically and stop using common sense. Usually a direct result of watching too much Fox News.
Announcer: This is Skeeter.

Skeeter: Kenyan, Muslim, Communist, Socialist.

Announcer: Skeeter is suffering from Obama Derangement Syndrome.

Skeeter: He bowed to other world leaders. He had a hip-hop barbecue.
door potterfreak98 24 oktober 2012
When a person stops disagreeing with Obama on political policy and believe every single policy decision that he make is apart sinister conspiracy to weaken or destroy America and possibly the world.
"Obama will confiscate guns, bring the Muslim brotherhood to power in America, Take all his orders from Putin, declare war on Israel, become a permanent dictator, maybe even become the anti Christ and set up a one world government...But I just disagree with the guy. How an I suffering from Obama Derangement Syndrome?"
door Lexington50 2 december 2012
Insane state of mind and lack of critical thinking or reasoning on issues surrounding Sen. Barack Obama's bid for the 2008 White House; usually used in reference towards his supporters.
After listening to Sen. Barack Obama's speech, I couldn't help but think that everyone had lost their minds and had come down with Obama Derangement Syndrome.
door flyfish 27 februari 2008
A derogatory term used for the act of critical thinking about Barack Obama. This term is derived from BDS, Bush Derangement Syndrome.
"He accused me of having Obama Derangement Syndrome because I asked if Obama had ever accomplished anything!"
door lolbama 29 oktober 2008

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