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1.
OTS
One Take Session. To record a video or audio clip in one continuous take without any cuts.

Gabe Bondoc does many OTSs on youtube.
Gina: "I want people to know that I can actually sing well without studio effects and autotune."

Zack: "Then let's do an OTS of a song you want to sing and put it on our youtube channel."
door youmakemyslackstighter 10 juli 2010
 
2.
OTS
Plain & simple - OTS is Off that Shit ! Or "on one".
Wow, look at him go ! He's OTS for sure !
door Jayare a.k.a. goo1z 27 mei 2007
 
3.
OTS
On The Side

Meaning having a person on the side other than your significant other.
"Wow Mike is taking a very long lunch today with his OTS."
door infestacool 5 februari 2009
 
4.
OTS
Off the shits.

High as fuck
Drunk
Trippy
Fucked up
Boy we smoked 8 loud blunts, you know I was OTS .

MY nigga you off the shits

You off the shits breh

I'm tryna get ots . you wanna match ?
door Kiddoe Kwasiee 20 februari 2014
 
5.
OTS
ON THE SACK!
THAT BITCH IS OTS!
door GORILLA PIMPIN 7 juni 2010
 
6.
OTS
"Oh the Shame" like if you shit your pants or you dropped the dutchie
Guy1: Oh shit man, I dropped the last water bong Bob Marley ever used!!
Guy2: You dick! Everyone will hate you forever
Guy1: OTS TT~TT
door Incredible Chemical 11 augustus 2010
 
7.
OTS
Off The Spectrum. Kinda like Off The Hook, or Off the Snuggies, but better because it's Spectrum. Usually refers to the visible light region of the electromagnetic spectrum.
This party is OTS!
door wizrdry 10 juni 2009