What you call someone who has recently been an idiot, asked an extremely stupidass question or is just a flat-out moron.
Person one: hey look at me i'm licking the floor

Person two: ... do you have fucking down syndrome?

Person one: is the Earth flat?

Person two: you have down syndrome.
door Knee-Grow10 17 april 2007
an insult, to say to ones friends when they are acting 'crippled'
Clutch, are you fuckin down syndrome!
door 106_joN 27 maart 2005
A phrase used to make fun of someone after they have done something stupid. Also, a disease similar to mental retardation. Many people who have down syndrome have competed in the Special Olympics.
What the hell is your problem! Are you down syndrome or something?
door J-dog 9 april 2005
very strange...and exessively weird
cara is the coolest kid with down syndrome i know
door ilovematthew 8 mei 2006

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